Adrian Danek Selected Research

tau Proteins (tau Protein)

1/2021	Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis.
1/2019	PET Imaging of Astrogliosis and Tau Facilitates Diagnosis of Parkinsonian Syndromes.
1/2017	[18F]-THK5351 PET Correlates with Topology and Symptom Severity in Progressive Supranuclear Palsy.

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Adrian Danek Research Topics

Disease

21	Frontotemporal Dementia (Semantic Dementia) 01/2023 - 02/2010
19	Alzheimer Disease (Alzheimer's Disease) 11/2023 - 12/2015
18	Neuroacanthocytosis 01/2023 - 08/2002
11	Dementia (Dementias) 11/2023 - 11/2011
10	Atrophy 07/2023 - 12/2007
9	Disease Progression 01/2023 - 01/2017
9	Cognitive Dysfunction 01/2023 - 09/2015
9	Movement Disorders (Movement Disorder) 02/2022 - 08/2005
8	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2023 - 12/2012
5	Parkinson Disease (Parkinson's Disease) 11/2023 - 07/2008
5	Neuroinflammatory Diseases 07/2023 - 10/2020
5	Mcleod Type Neuroacanthocytosis 01/2023 - 08/2002
5	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2023 - 12/2017
4	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2023 - 01/2017
4	Down Syndrome (Down's Syndrome) 09/2022 - 11/2014
4	Abetalipoproteinemia (Bassen Kornzweig Syndrome) 02/2022 - 10/2008
4	Corticobasal Degeneration 01/2021 - 01/2017
4	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2020 - 01/2017
4	Primary Progressive Aphasia 01/2019 - 03/2014
3	Parkinsonian Disorders (Parkinsonism) 11/2023 - 02/2013
3	Dystonia (Limb Dystonia) 02/2022 - 01/2014
3	Chorea (Rheumatic Chorea) 02/2022 - 08/2002
3	Gliosis 01/2022 - 01/2019
3	Seizures (Absence Seizure) 12/2019 - 05/2011
3	Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease) 11/2018 - 10/2011
2	Multiple System Atrophy 11/2023 - 01/2019
2	Epilepsy (Aura) 02/2022 - 01/2022
2	Peripheral Nervous System Diseases (PNS Diseases) 02/2022 - 08/2002
2	Multiple Sclerosis 01/2022 - 01/2022
2	Basal Ganglia Diseases (Basal Ganglia Disease) 11/2021 - 05/2011
2	Tauopathies 11/2021 - 01/2021
2	Amyloidosis 01/2021 - 09/2015
2	Cerebellar Ataxia (Dysmetria) 01/2019 - 09/2011
2	Hypobetalipoproteinemias (Hypobetalipoproteinemia) 11/2018 - 10/2011
2	Muscular Diseases (Myopathy) 12/2012 - 08/2002
1	Cardiomyopathies (Cardiomyopathy) 02/2022
1	Confusion (Bewilderment) 02/2022
1	Dizziness (Lightheadedness) 01/2022
1	Stroke (Strokes) 01/2022
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2022
1	Central Nervous System Vasculitis 12/2021
1	Cerebral Cortical Thinning 01/2021
1	Myoclonus (Nocturnal Myoclonus) 12/2019
1	Mental Disorders (Mental Disorder) 01/2019
1	Nervous System Diseases (Neurological Disorders) 11/2018
1	Rare Diseases (Rare Disease) 11/2018
1	Huntington Disease-Like 2 11/2018

Drug/Important Bio-Agent (IBA)

26	Biomarkers (Surrogate Marker)IBA 11/2023 - 01/2017
14	Proteins (Proteins, Gene)FDA Link 01/2023 - 10/2011
13	Amyloid (Amyloid Fibrils)IBA 07/2023 - 12/2016
7	Creatine Kinase (Creatine Phosphokinase)IBA 02/2022 - 08/2002
6	ProgranulinsIBA 01/2023 - 02/2010
5	Glucose (Dextrose)FDA LinkGeneric 11/2023 - 01/2017
4	GranulinsIBA 01/2022 - 01/2021
4	Lipoproteins (Lipoprotein)IBA 11/2021 - 08/2002
3	Glial Fibrillary Acidic ProteinIBA 01/2022 - 01/2019
3	Phosphotransferases (Kinase)IBA 01/2021 - 11/2011
3	tau Proteins (tau Protein)IBA 01/2021 - 01/2017
2	Dopamine (Intropin)FDA LinkGeneric 11/2023 - 01/2020
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2023 - 08/2022
2	beta-SynucleinIBA 01/2023 - 01/2022
2	neuronal pentraxinIBA 01/2022 - 01/2020
2	Protein Isoforms (Isoforms)IBA 11/2021 - 01/2021
2	SynucleinsIBA 01/2021 - 01/2019
2	THK5351IBA 01/2019 - 01/2017
2	Membrane Proteins (Integral Membrane Proteins)IBA 12/2016 - 04/2011
2	Cholinergic Agents (Cholinergics)IBA 10/2016 - 03/2014
2	Apolipoproteins E (ApoE)IBA 09/2015 - 11/2014
2	Indicators and Reagents (Reagents)IBA 09/2015 - 02/2011
1	Complement System Proteins (Complement)IBA 09/2022
1	LipidsIBA 02/2022
1	tributyl phosphate (TBP)IBA 01/2022
1	nasIBA 01/2022
1	ponceau 4R (E 124)IBA 01/2022
1	BNT162 VaccineIBA 01/2022
1	RNA Splice SitesIBA 01/2022
1	TATA-Box Binding Protein (TATA-Binding Protein)IBA 01/2022
1	Dasatinib (BMS 354825)FDA Link 12/2021
1	Amphetamine (Amfetamine)FDA LinkGeneric 12/2021
1	Protein AggregatesIBA 01/2021
1	LigandsIBA 01/2021
1	nilotinib FDA Link 01/2021
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2021
1	Amyloid beta-PeptidesIBA 01/2021
1	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2020
1	ioflupaneIBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Amino Acids FDA Link 12/2019
1	Donepezil (Aricept)FDA LinkGeneric 12/2019
1	Cytoskeletal ProteinsIBA 01/2019
1	Monoamine Oxidase (MAO)IBA 01/2019
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2019
1	HDL2 LipoproteinsIBA 11/2018
1	Familial apoceruloplasmin deficiencyIBA 11/2018
1	chitotriosidaseIBA 01/2018

Therapy/Procedure

4	Deep Brain Stimulation 11/2011 - 07/2008
1	Activities of Daily Living (ADL) 01/2023
1	Hemodiafiltration 01/2022
1	Palliative Care (Palliative Therapy) 01/2022
1	Duration of Therapy 01/2019